At ReadCoor, we envision swifter scientific discoveries, disease diagnosis and drug development from sequencing reads enhanced by panomic spatial data.
Current next-generation sequencing methods require the structural breakdown of samples to identify molecular targets of interest. Grinding samples into fragments is the conventional method scientists use to identify the nucleic sequences of a sample. Although this process provides researchers with a list of sequences, the corresponding spatial data associated with the sequences is lost.
Spatial sequencing methods focus on the preservation of locational data to identify molecule coordinates and provide insight into the relational nature of molecules and cells. By identifying the three-dimensional coordinates of molecular targets, spatial sequencing provides a more robust understanding of the dynamic cellular and molecular forces that contribute to health, disease, and cell development. This level of detail can help scientists begin to advance our understanding of the neighboring influences of co-cultured cancer cells or the nexus of cancerous and healthy tissue, among many other scientific and clinical insights.
ReadCoor’s spatial sequencing technology, Fluorescent in situ Sequencing (FISSEQ), provides further scientific insight in the form of panomic readouts that capture cell morphology. Reads from FISSEQ are presented in a 3D image of molecular targets in tissue or cell samples. The high level of detailed cellular and molecular information captured through the FISSEQ platform provides researchers more data-enriched reads contributing to accelerated discoveries, diagnosis and treatment.